山东大学生命科学学院导师：庞秀华 正文

　　庞秀华
　　博士生导师
　　
　　教育背景
　　1985-1989 山东师范大学，学士
　　1989-1992 中国科学院武汉病毒研究所，硕士
　　1996-2000 华中农业大学，博士
　　2001-2004 博士后, Faculté des Sciences et Techniques, Nancy Université, France。
　　2004-2009 讲师(Instructor)，Center for Pulmonary and Infectious Disease Control, University of Texas Health Science Center at Tyler
　　
　　研究成果及发表论文
　　1.Pang X, Sun Y, Liu J, Zhou X, Deng Z. 2002. A linear plasmid temperature-sensitive for replication in Streptomyces hygroscopicus 10-22. FEMS Microbiological Letter. 208:25-8.
　　2.Pang X, Zhou X, Sun Y, Deng Z. 2002. Physical map of the linear chromosome of Streptomyces hygroscopicus 10-22 deduced by analysis of overlapping large chromosomal deletions. Journal of Bacteriology. 184:1958-65.
　　3.Pang X, Aigle B, Girardet JM, Mangenot S, Pernodet JL, Decaris B, Leblond P. 2004. Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome. Antimicrobial Agents and Chemotherapy. 48:575-88.
　　4.Aigle B, Pang X, Decaris B, Leblond P. 2005. Involvement of AlpV, a new member of the Streptomyces antibiotic regulatory protein family, in the regulation of the duplicated type II polyketide synthase alp gene cluster in Streptomyces ambofaciens. Journal of Bacteriology. 187(7): 2491-2500. Pang X and Aigle B contributed equally in this work
　　5.Jian X, Pang X, Zhou X, Deng Z. 2006. Identification of genes necessary for jinggangmycin biosynthesis from Streptomyces hygroscopicus 10-22. Antonie van Leeuwenhoek. 90(1):29-39. Pang X and Jian X contributed equally in this work
　　6.Howard S, Recht J, Alsup A, Pang X, Kolter R, Lyons CR, Byrd T. 2006. Spontaneous reversion of Mycobacteium abscessus from a smooth to a rough morphotype is associated with loss of glycopeptidolipid and reacquisition of an invasive phenotype. Microbiology. 152:1581-90.
　　7.Pang X., Vu P., Byrd T.F., Ghanny S., Soteropoulos P., Mukamolova G.V., Wu S., Samten B.,Howard S.T. 2007. Evidence for complex interactions of stress-associated regulons in an mprAB deletion mutant of Mycobacterium tuberculosis. Microbiology. 153:1229-1242.
　　8.Pang X. and Howard S.T. 2007. Regulation of the alpha-crystallin gene acr2 by the MprAB two-component signal transduction system of Mycobacterium tuberculosis. Journal of Bacteriology. 189:6213-6221.
　　9.Robert Bunet, Marta V. Mendes, Nicolas Rouhier, Pang X, Laurence Hotel, Pierre Leblond, and Bertrand Aigle. 2008. Regulation of the synthesis of the angucyclinone antibiotic alpomycin in Streptomyces ambofaciens by the autoregulator receptor AlpZ and its specific ligand. Journal of Bacteriology. 190(9):3293-305.
　　10.Wu S, Peter F. Barnes, Samten B, Pang X, Rodrigue S, Gaudreau L, Ghanny S, Soteropoulos P, and Howard S. 2009. Eis protein of Mycobacterium tuberculosis is regulated by SigA and required for growth in macrophage. Microbiology. 155:1272-1281
　　11.Peter Klucar, Peter F. Barnes, Ying Kong, Susan Howard, Pang X, Fang-Fang Huang, Amy Tvinnereim, Buka Samten and Homayoun Shams. 2009. Vaccination Strategies to Enhance Mucosal Immunity and Protection against Mycobacterium tuberculosis. Vaccine. 27:1816-1824.

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