教育背景/经历　Education

2002.6 吉林大学 生物制药 本科
2009.1-2009.6 中科院生化细胞所 生物化学与分子生物学 博士研究生
2016.2 美国韦恩州立大学 药学工程 博士后

工作经历　Work Experience

2016.2 – 至今，东莞理工学院机械工程学院骨干A引进人才。

科研情况　Scientific

Serine/Threonine Protein Phosphatase 1 in Insulin Resistance and Type 2 diabetes. R01.于2015年2月递交至NIH/NIDDK. 获5年资助，共计2,583,343  美元。
HUMAN SKELETAL MUSCLE PROTEOME AND PHOSPHOPROTEOME IN OBESITY AND TYPE 2 DIABETES. R01. 获5年资助，共计3,387,343  美元。

出版物　Publications

1. Proteomics analyses of subcutaneous adipocytes reveal novel abnormalities in human insulin resistance. Xie X, Yi Z, Sinha S, Madan M, Bowen BP, Langlais P, Ma D, Mandarino L, Meyer C. Obesity (Silver Spring). 2016 Jul;24(7):1506-14. doi: 10.1002/oby.21528.
2. Quantitative proteomics reveals novel protein interaction partners of PP2A catalytic subunit in pancreatic β-cells. Zhang X, Damacharla D, Ma D, Qi Y, Tagett R, Draghici S, Kowluru A, Yi Z. Mol Cell Endocrinol. 2016 Mar 15;424:1-11. doi: 10.1016/j.mce.2016.01.008. Epub 2016 Jan 9.
3. Novel Endogenous, Insulin-Stimulated Akt2 Protein Interaction Partners in L6 Myoblasts. Caruso M, Zhang X, Ma D, Yang Z, Qi Y, Yi Z. PLoS One. 2015 Oct 14;10(10):e0140255. doi: 10.1371/journal.pone.0140255. eCollection 2015.
4. Optimization of Search Engines and Postprocessing Approaches to Maximize Peptide and Protein Identification for High-Resolution Mass Data. Tu C, Sheng Q, Li J, Ma D, Shen X, Wang X, Shyr Y, Yi Z, Qu J. J Proteome Res. 2015 Nov 6;14(11):4662-73. doi: 10.1021/acs.jproteome.5b00536. Epub 2015 Sep 30.
5. Quantitative phosphoproteomics reveals novel phosphorylation events in insulin signaling regulated by protein phosphatase 1 regulatory subunit 12A. Zhang X, Ma D, Caruso M, Lewis M, Qi Y, Yi Z. J Proteomics. 2014 Sep 23;109:63-75. doi: 10.1016/j.jprot.2014.06.010. Epub 2014 Jun 25.
6. Increased interaction with insulin receptor substrate 1, a novel abnormality in insulin resistance and type 2 diabetes. Caruso M, Ma D, Msallaty Z, Lewis M, Seyoum B, Al-janabi W, Diamond M, Abou-Samra AB, Højlund K, Tagett R, Draghici S, Zhang X, Horowitz JF, Yi Z. Diabetes. 2014 Jun;63(6):1933-47. doi: 10.2337/db13-1872. Epub 2014 Feb 28.
7. Novel Aquatic Silk Genes from Simulium (Psilozia) vittatum (Zett) Diptera: Simuliidae.Papanicolaou A, Woo A, Brei B, Ma D, Masedunskas A, Gray E, Xiao GG, Cho S, Brockhouse C. Insect Biochem Mol Biol. 2013 Oct 24. pii: S0965-1748(13)00185-9. doi: 10.1016/j.ibmb.2013.09.008. [Epub ahead of print]
8. Mdig de-represses H19 large intergenic non-coding RNA (lincRNA) by down-regulating H3K9me3 and heterochromatin. Chen B, Yu M, Chang Q, Lu Y, Thakur C, Ma D, Yi Z, Chen F. Oncotarget. 2013 Sep;4(9):1427-37.
9. Inhibition of transketolase by oxythiamine altered dynamics of protein signals in pancreatic cancer cells. Wang J, Zhang X, Ma D, Lee WN, Xiao J, Zhao Y, Go VL, Wang Q, Yen Y, Recker R, Xiao GG. Exp Hematol Oncol. 2013 Jul 27;2:18. doi: 10.1186/2162-3619-2-18. eCollection 2013.
10. SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion. Chen XW, Wang H, Bajaj K, Zhang P, Meng ZX, Ma D, Bai Y, Liu HH, Adams E, Baines A, Yu G, Sartor MA, Zhang B, Yi Z, Lin J, Young SG, Schekman R, Ginsburg D. Elife. 2013 Apr 9;2:e00444. doi: 10.7554/eLife.00444.
11. Smoke-induced signal molecules in bone marrow cells from altered low-density lipoprotein receptor-related protein 5 mice. Ma D, Li Y, Hackfort B, Zhao Y, Xiao J, Swanson PC, Lappe J, Xiao P, Cullen D, Akhter M, Recker R, Xiao GG. J Proteome Res. 2012 Jul 6;11(7):3548-60. doi: 10.1021/pr2012158. Epub 2012 Jun 4.
12. Site-specific phosphorylation of protein phosphatase 1 regulatory subunit 12A stimulated or suppressed by insulin. Chao A, Zhang X, Ma D, Langlais P, Luo M, Mandarino LJ, Zingsheim M, Pham K, Dillon J, Yi Z. J Proteomics. 2012 Jun 18;75(11):3342-50. doi: 10.1016/j.jprot.2012.03.043. Epub 2012 Apr 6.
13. Inhibition of glycogen phosphorylation induces changes in cellular proteome and signaling pathways in MIA pancreatic cancer cells. Ma D, Wang J, Zhao Y, Lee WN, Xiao J, Go VL, Wang Q, Recker RR, Xiao GG. Pancreas. 2012 Apr;41(3):397-408. doi: 10.1097/MPA.0b013e318236f022.

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